Esophageal pH Monitoring Abnormalities and Gastroesophageal Reflux Disease in Infants With Intestinal Malrotation

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Esophageal pH monitoring abnormalities and gastroesophageal reflux disease in infants with intestinal malrotation.

HYPOTHESIS Infants with rotational abnormalities of the midgut mesentery are at high risk for gastroesophageal reflux disease (GERD) and for sudden infant death (SID) from GERD. DESIGN A survey of the prevalence of GERD and the risk factor for SID from GERD in a case series of infants treated for congenital anomalies that include intestinal malrotation. Eighty-one (89%) of the infants studied...

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Esophageal Manometry and 24-Hour pH Monitoring to Evaluate Laparoscopic Lind Fundoplication in Gastroesophageal Reflux Disease

Laparoscopic and thoracoscopic techniques have provided a new dimension in the correction of functional disorders of the esophagus. Therapeutic success, however, depends on the confirmation of esophageal disease as a cause of the symptoms, on understanding the basic cause of dysfunction and on identifying the surgical patient. This study is a retrospective study of patients submitted to surgery...

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Generation of Gastroesophageal Reflux Disease Symptoms During Esophageal Acid Infusion With Concomitant Esophageal pH Monitoring in Healthy Adults

BACKGROUND/AIMS The sensitivity of the upper and lower esophageal mucosa to acid is considered to differ. We investigated the relationship between pH changes in different sites of the esophagus and generation of gastroesophageal reflux symptoms during an acid infusion test. METHODS An acid infusion catheter was placed at 5 or 15 cm above the lower esophageal sphincter (LES) in 18 healthy volu...

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Research on Gastroesophageal Reflux Disease Based on Dynamic Features of Ambulatory 24-Hour Esophageal pH Monitoring

Ambulatory 24-hour esophageal pH monitoring has been considered as the gold standard for diagnosing gastroesophageal reflux disease (GERD), and in clinical application, static parameters are widely used, such as DeMeester score. However, a shortcoming of these static variables is their relatively high false negative rate and long recording time required. They may be falsely labeled as nonreflux...

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Gastroesophageal reflux disease in infants and children.

Gastroesophageal reflux (GER), represents the retrograde movement of gastric contents into the esophagus, and is a frequently experienced benign but symptomatic condition. At the one end of the spectrum are infants with physiologic reflux, also referred to in the United States as “happy spitters”, and at the other end are children with objective pathologic sequelae comprising gastroesophageal r...

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ژورنال

عنوان ژورنال: Archives of Surgery

سال: 1999

ISSN: 0004-0010

DOI: 10.1001/archsurg.134.7.747